Terbium-161 produced at the highest radiochemical grade under non-GMP conditions, available in 0.05M HCl Solution. Current intended use: not for direct administration to humans.
Carrier-free lanthanide (NCA) Terbium-161 is produced by neutron activation of the highly enriched Gadolinium-160 using small and medium research reactors. As a promising radionuclide for Radioligand Therapy, Terbium-161 exhibits comparable chemical characteristics to known radiolanthanides allowing utilization of current radiolabeling techniques.
From a clinical perspective, early research suggests improved anti-tumor capabilities, especially for (micro)metastasized cancers, owing to an increase in emission of Auger and conversion electrons when using terbium-161 compared to other known radiolanthanides.
Allowing optimization of the SPECT reconstruction parameters, Terbium-161 may provide for higher spatial resolution SPECT imaging, leading to the detection of smaller lesions that provides input for a further optimized treatment plan.